Pectin hydrogels, aerogels, cryogels and xerogels: Influence of drying on structural and release properties

Pectin is an appealing material for biomedical applications because of its biocompatibility, bioactivity, biodegradability as well gelling and stabilizing properties. In this work, porous pectin cryogels, aerogels xerogels were prepared via freeze-drying, sc drying evaporative at 60 °C under low vacuum, respectively, starting from the same precursor, a hydrogel. The physico-chemical structural properties matrices investigated related to preparation conditions. release model hydrophilic respiratory drug theophylline all networks, including hydrogel, was studied network morphology erosion profiles. Korsmeyer-Peppas Peppas-Sahlin models used determine main physical mechanisms controlling release. can be tuned mode crosslinking in initial hydrogel method, demonstrating potential delivery purposes.